Uniformed Services University of the Health Sciences
Department of Pathology
4301 Jones Bridge Road, C1094
Bethesda, Maryland 20814-4799
Room: B3154
Phone: (301) 295-3450
fax: (301) 295-1640
Charles S. Via, M.D.
Professor
Email: charles.via@usuhs.edu
curriculum vitae
Education
- B.A.(with honors), Psychology, University of Virginia, Charlottesville, VA, 1969
- M.D., University of Virginia Medical School, Charlottesville, VA 22908, 1973
Current Research Interests:
T cell function in lupus, immology of graft-vs-host disease and in vivo immunomodulation.
Selected Publications
Via CS, Shustov A, Rus V, Lang T, Nguyen P, Finkelman FD. In vivo neutralization of TNF-alpha promotes humoral autoimmunity by preventing the induction of CTL. J. Immunol. 167:6821-6826, 2001.
Rus V, Atamas SP, Shustova V, Luzina IG, Selaru F, Magder LS, Via CS. Expression of cytokine- and chemokine-related genes in peripheral blood mononuclear cells from lupus patients by cDNA array. Clin. Immunol. 102:283-90, 2002.
Via CS, Nguyen P, Niculescu F, Papadimitriou J, Hoover D, Silbergeld EK. Low dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupus. Environ. Health Perspect. 111:1273-7, 2003.
Lang TJ,Nguyen P, Papadimitriou J, Via CS. Increased severity of murine lupus in female mice is due to enhanced expansion of pathogenic T cells. J. Immunol. 171:5795-801, 2003.
Puliaev R, Nguyen P, Finkelman F, Via CS. Differential requirements for interferon-in CTL maturation in acute GVHD. J. Immunol. 173:910-919, 2004.
Grader-Beck T, Casciola-Rosen L, Lang T, Rosen A, Via CS. Apoptotic splenocytes drive the autoimmune response to poly (ADP-ribose) polymerase 1 in a murine model of lupus. J. Immunol. 178:95-102, 2007.
Rus V, Nguyen V, Puliaev R, Puliaeva I, Zernetkina V, Luzina I, Papadimitriou JC, Via CS. T cell TRAIL promotes murine lupus by sustaining CD4 T cell help for B cells and inhibiting CD8 cytotoxic T lymphocyte activity. J. Immunol. 178(6):3962-72, 2007.
