Image Processing Core


Located on the NIH Bethesda Campus, Clinical Center Building 10, Room B1N264.B


  • Data anonymization and quality control
  • DICOM-compliant image data repository
  • Standard image pre-processing and manipulation
  • Image registration and fusion for enhanced visualization
  • Quantitative structural image analysis
  • Localization of lesions and other regions of brain injury

Data Processed

Includes structural and functional MRI, diffusion tensor MRI, perfusion MRI, computed tomography (CT), and positron emission tomography (PET).

Processing Capabilities

  • Multimodal rigid-body, affine, and deformable image registration
  • Volumetrics for whole brain, total gray matter, total white matter, sulcal and ventricular cerebrospinal fluid volumes, cerebrum, cerebellum, thalamus, putamen, caudate nucleus, brainstem, hippocampus, amygdala, and lesions
  • Cortical thickness measurements for lobar or specific gyral regions
  • Diffusion tensor fiber tracking
  • Fractional anisotropy, mean diffusivity, apparent diffusion coefficient measurements for whole brain, lobes, or white matter tracts
  • Voxel-based morphometry
  • Satistical parametric mapping for functional imaging
  • Tract based spatial statistics
  • Cerebral blood flow, cerebral blood volume, and mean transit time mapping from dynamic susceptibility contrast MRI.

Standard Operating Procedures

Data transfer may be performed through DICOM send/retrieve or secure file transfer protocols. Contact the core director for details and applicable services.

Points of contact for information on core resources, policies, and procedures

Access to the use of these cores is subject to CNRM review and chargeback fees may apply.