Agenda

The IRIS-2011 Symposium will be held in Lecture Hall D at the Uniformed Services University of the Health Sciences (USUHS) on the grounds of the National Naval Medical Center (NNMC), Bethesda, Maryland (directions).

Day 1—Thursday, May 12, 2011

Time	Event
7:30 a.m.	Registration
8:00 a.m.	Welcome Dr. Charles Rice, President, USUHS
8:10 a.m.	Opening Remarks COL Mark A. Melanson, Director, AFRRI
8:20 a.m.	Introduction Dr. Adarsh Ramakumar, Chairman, IRIS

Session 1—Radiation Biology: The Science

Chairs: Drs. William F. Blakely and Carolyn J. Fisher

Time	Event
8:30 a.m.	Radiation biology—From the past 50 years to the next 50 years! Dr. K. Sree Kumar, Principal Investigator & Sr. Scientist, AFRRI, Bethesda, MD
8:55 a.m.	Low dose radiation research: What we have learned? Dr. Noelle Metting, Program Manager, Radiobiology, OBER/DOE, Washington, DC
9:20 a.m.	Radiobiological basis of radiation protection: Standards and inter-laboratory exercises for emergency preparedness Dr. Ruth Wilkins, Sr. Scientist Radiobiology, Consumer and Clinical Radiation Protection Bureau, Health Canada, Ottawa, Canada
9:45 a.m.	Japan radiation incident: A firsthand account of managing a radiation emergency response Professor Mitsuaki Yoshida, Department of Radiation Biology, Institute of Radiation Emergency Medicine, Hirosaki University, Hirosaki, Japan
10:10 a.m.	Break

Session 2—'Omics for Radiation Biology

Chairs: Drs. John F. Kalinich and Sanchita P. Ghosh

Time	Event
10:30 a.m.	Proteomics for radiation biomarker discovery Professor Harvey Pollard, Chair, Department of Anatomy, Physiology and Genetics, USUHS, Bethesda, MD
10:55 a.m.	Functional genomics for radiation biology: A gateway to understand cellular stress responses Professor Sally Amundson, Radiation Oncology, Center for Radiological Research, College of Physicians & Surgeons of Columbia University Medical Center, New York, NY
11:20 a.m.	Metabolomics for radiation biology Professor Albert Fornace, Jr., Molecular Cancer Research Chair at Lombardi Comprehensive Cancer Center; Professor, Department of Biochemistry and Molecular & Cellular Biology, and Dept. of Oncology, Georgetown, Washington, DC
11:45 a.m.	Lunch

Session 3—Applied Radiation Biology: Platforms and Technology

Chairs: Drs. Mark H. Whitnall and Shilpa S. Kulkarni

Time	Event
1:00 p.m.	Imageable nanoparticles for radiotherapy applications Dr. William T. Phillips, Nanoparticle Imaging/Therapeutic Systems, Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX
1:25 p.m.	Advances in translational radiation biology for improved cancer therapy and prevention from radiation exposure Professor David Boothman, Associate Director for Translational Research, University of Texas Southwestern Medical Center at Dallas, Dallas, TX
1:50 p.m.	Radiation-induced mitotic catastrophe: Role of RNA binding proteins Professor Shrikant Anant, Associate Director-Prevention and Cancer Control, Associate Dean for Research, University of Kansas School of Medicine, Kansas City, KS
2:15 p.m.	Development of novel therapeutic for the treatment of acute radiation syndrome Dr. Ram Mandalam, President and CEO, Cellerant Therapeutics, San Carlos, CA
2:40 p.m.	Break

Session 4—Artificial Intelligence and High-throughput Technologies for Radiation Biology

Chairs: Drs. Lynnette H. Cary and MAJ Eric D. Lombardini

Time	Event
3:00 p.m.	Need for infrastructure and high-throughput technologies to manage radiation data in a mass casualty Dr. Gordon Livingston, Technical Director, Cytogenetic Biodosimetry Laboratory, REAC/TS, ORISE & ORAU, Oak Ridge, TN
3:25 p.m.	Artificial Intelligence-assisted automated cytogenetics Dr. Adarsh Ramakumar, Principal Investigator & Sr. Bioinformatics, Biostatistics and Biomedical Analyst, AFRRI, Bethesda, MD
3:50 p.m.	Novel image segmentation approaches for automated identification of chromosome abnormalities due to radiation exposure Peter Rogan, Canada Research Chair in Genome Bioinformatics, Tier I, Professor of Biochemistry & Computer Science, University of Western Ontario, Ontario, Canada
4:15 p.m.	Nanoprobes and molecular high-throughput imaging approaches in theragnostics Dr. Rao Papineni, Sr. Principal Investigator, Research and Development, Carestream Molecular Imaging, Woodbridge, CT
4:40 p.m.	Adjourn

Day 2—Friday, May 13, 2011

Session 5—Technologies and Applications for Radiation Biology

Chairs: Drs. Juliann G. Kiang and CPT Ian C. Dews

Time	Event
7:30 a.m.	Registration
8:00 a.m.	Welcome and Day 2 Overview—Col L. Andrew Huff, Deputy Director, AFRRI
8:15 a.m.	Novel technology approaches for radiation repair Professor Chandan Guha, Vice Chair, Department of Radiation Oncology Montefiore Medical Center, Bronx, NY
8:40 a.m.	Predictive genomics: A post-genomic integrated approach to analyze biological signatures of radiation exposure Professor Prakash Hande, Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
9:05 a.m.	The advances of nanotechnology as applied to radiation biology Professor Sunil Krishnan, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX
9:30 a.m.	Mircofluidics applications for protein expression analysis and molecular diagnostics Dr. Seth Cohen, Senior Director, Microfluidic Applications & Support, Caliper Life Sciences, Hopkinton, MA
9:55 a.m.	Mircofluidics and advances in technology for radiation biology Professor Frederic Zenhausen, Director, Center for Applied Nanobioscience and Medicine, College of Medicine Phoenix, University of Arizona, Tucson, AZ
10:20 a.m.	Break

Session 6—Technology Blitz

Chairs: Drs. Michael Landauer and Lt Col Michael P. Dempsey

Time	Event
10:40 a.m.	Bioelectric strategies and applications for radiation biology Dr. Erik Young, Center for Radiological Research, Columbia University, New York, NY
11:05 a.m.	qNPA assay technology for gene expression signature development Dr. Bruce Seligmann, Chief Scientific Officer, High Throughput Genomics, Tucson, AZ
11:30 a.m.	Tools and advanced instrumentation for radiation biology data acquisition LTC Felicia Langel, VMD, PhD, Director, Biomedical Instrumentation Center, Uniformed Services University of Health Sciences, Bethesda, MD
11:55 a.m.	Harnessing cloud computing for Radioinformatics Dr. Ramesh Rangachar, Sr. Project Head, Intelsat, Washington, DC
12:20 p.m.	Lunch

Session 7—Governing the Science of Tomorrow!

Chairs: Drs. Pataje G.S. Prasanna and Richard Levine

Time	Event
1:40 p.m.	Overview of DOE systems biology knowledge base and initiatives Dr. Susan Gregurick, Program Director, OBER/DOE, Washington DC
2:00 p.m.	Overview of Biomedical Advanced Research and Development Authority (BARDA) programs Dr. Richard Hatchet, Chief Medical Officer & Deputy Director, HHS/OS/ASPR/ BARDA, Washington, DC
2:20 p.m.	Overview of NIAID’s Radiation/Nuclear Medical Countermeasures Development Program Dr. Bert Maidment, Associate Director, Product Development NIAID/NIH, Rockville, MD
2:40 p.m.	Overview and policy of Office of Assistant Secretary for Preparedness and Response, USA Dr. Maria Julia Marinissen, Director, Division of International Health Security, HHS, Washington DC
3:00 p.m.	Break

Time	Event
3:20 p.m.	Panel discussion: Forming the road map for Radioinformatics application development A six member panel of distinguished people will be announced separately. Convenor: Dr. Christopher Lissner, Scientific Director, AFRRI
5:00 p.m.	Closing remarks COL Mark A. Melanson, Director, AFRRI
5:10 p.m.	Vote of thanks Dr. Adarsh Ramakumar, Chairman, IRIS

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